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EXED-003B
Exendin-4
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Size:1.0mg
P1(RMB):1134
MW:4186.7
One letter sequence:HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
Molecular Formula:C184H282N50O60S1
Description:Exendin-4, originally isolated from Heloderma suspectum venom, stimulates acinar cAMP without causing amylase release, binds with similar affinity to the glucagon-like peptide 1 receptor, and is used in the treatment of type 2 diabetes.
Literature Reference:J. Eng et al., J. Biol. Chem., 267(11), 7402 (1992)
Cas:[141758-74-9]
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