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NEUP-008A
Neuromedin S (rat)
Leu-Pro-Arg-Leu-Leu-His-Thr-Asp-Ser-Arg-Met-Ala-Thr-Ile-Asp-Phe-Pro-Lys-Lys-Asp-Pro-Thr-Thr-Ser-Leu-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2 Trifluoroacetate salt
Size:0.5mg
P1(RMB):847
MW:4241.98
One letter sequence:LPRLLHTDSRMATIDFPKKDPTTSLGRPFFLFRPRN-NH2
Molecular Formula:C193H307N57O49S
Description:A neuromedin U-related neuropeptide specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. rNMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. rNMS showed potent anorexigenic effects and counteracted neuropeptide Y, ghrelin and agouti-related protein-induced food intake. This compound is distributed through Peptide Institute, Inc. under the license of National Cardiovascular Center and Takeda Pharmaceutical Company Limited
Literature Reference:T.Ida et al., Endocrinology, 146, 4217 (2005) K.Mori et al., EMBO J., 24, 325 (2005)
Cas:843782-19-4
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