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RENI-012
Renin 390 FRET Substrate I
Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg
Size:1mg
P1(RMB):830
MW:2282.7
One letter sequence:R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
Molecular Formula:
Description:This peptide is a renin substrate (angiotensinogen) labeled with EDANS/ DABCYL FRET pair for renin activity studies. The renin-angiotensin system (RAS), acting through type 1 angiotensin (AT1) receptors, is a master regulator of fluid homeostasis.
Literature Reference:Crowley, S. et al. J. Clin. Invest. 115, 1092 (2005); Holzman, T. et al. J. Protein Chem. 9, 663 (1990).
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